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Oxandrolone is indicated as adjunctive therapy to offset the protein catabolism associated with prolonged administration of corticosteroids, and for the relief of the bone pain frequently accompanying osteoporosis (see DOSAGE AND ADMINISTRATION ). Drug Abuse and Dependence. Oxandrolone is classified as a controlled substance under the Anabolic Steroids Control Act of 1990 and has been assigned to Schedule III (non-narcotic). Known or suspected carcinoma of the prostate or the male breast. Carcinoma of the breast in females with hypercalcemia (androgenic anabolic steroids may stimulate osteolytic bone resorption). Pregnancy, because of possible masculinization of the fetus. Oxandrolone has been shown to cause embryotoxicity, fetotoxicity, infertility, and masculinization of female animal offspring when given in doses 9 times the human dose. Nephrosis, the nephrotic phase of nephritis. Cholestatic hepatitis and jaundice may occur with 17-alpha-alkylated androgens at a relatively low dose, sustanon 250 effect. If cholestatic hepatitis with jaundice appears or if liver function tests become abnormal, Oxandrolone should be discontinued and the etiology should be determined. Drug-induced jaundice is reversible when the medication is discontinued. In patients with breast cancer, anabolic steroid therapy may cause hypercalcemia by stimulating osteolysis. Oxandrolone therapy should be discontinued if hypercalcemia occurs. Edema with or without congestive heart failure may be a serious complication in patients with pre-existing cardiac, renal, or hepatic disease. Concomitant administration of adrenal cortical steroid or ACTH may increase the edema. In children, androgen therapy may accelerate bone maturation without producing compensatory gain in linear growth. This adverse effect results in compromised adult height. The younger the child, the greater the risk of compromising final mature height. The effect on bone maturation should be monitored by assessing bone age of the left wrist and hand every 6 months (see PRECAUTIONS, Laboratory Tests ). Geriatric patients treated with androgenic anabolic steroids may be at an increased risk for the development of prostatic hypertrophy and prostatic carcinoma. ANABOLIC STEROIDS HAVE NOT BEEN SHOWN TO ENHANCE ATHLETIC ABILITY. Concurrent dosing of Oxandrolone and warfarin may result in unexpectedly large increases in the International Normalized Ratio (INR) or prothrombin time (PT). When Oxandrolone is prescribed to patients being treated with warfarin, doses of warfarin may need to be decreased significantly to maintain the desirable INR level and diminish the risk of potentially serious bleeding ( see PRECAUTIONS, Drug Interactions). Women should be observed for signs of virilization (deepening of the voice, hirsutism, acne, clitoromegaly). Discontinuation of drug therapy at the time of evidence of mild virilism is necessary to prevent irreversible virilization. undefined Low testosterone may affect the desire for sex, but it rarely causes ed. Testosterone replacement therapy has many risks. Testosterone treatment can cause the. — this drug is also taken by athletes and bodybuilders for as it has an anabolic effect. A boost in testosterone levels in the body naturally. Order sustanon 250 mg injection (1) online & get flat 18% off on pharmeasy. Read about the uses, dosage, treatment, side-effects & faqs. Sustanon 250 side effects — it replicates the muscle-building and strength-enhancing effects of testosterone (sustanon 250), but without the unwanted. It comes as a patch (androderm), injection (depo-testosterone, sustanon 250, reandron) or capsules. — sustanon-250 is a very good choice during the off-season or for those planning a bulking cycle. 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