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Colony collapse disorder (CCD) is a syndrome in which entire colonies of honey bees experience rapid decline and, eventually, complete destruction. Causes of the condition are not fully defined, but at least part of the problem can be contributed to an infection in honey bee guts by the fungus Nosema ceranae. By supplementing the food that honey bees eat with BPC-157, researchers have shown a reduction in the damage the fungus causes in honey bee GI tracts and a concomitant increase in hive survival rates [16]. These trials were carried out in natural field settings and offer the first significant oral treatment for reducing the impact of CCD on the most important pollinator for most food crops. BPC-157 is under active investigation in a number of cell culture and animal models. 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