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This system involved the administration of anabolic steroids on rats, either orally or by injection (depending on the anabolic steroid being assessed)for 3 days. The administration of anabolic steroids increased the weight of the rats and caused significant increases in the size of the brain and heart. The anabolic steroids tended to decrease the number of mitochondria and increases in the number of cells was not observed. It is believed that this study indicates the use on rats of steroids can lead to changes in the number and structure of the cells of the body. This study also found that a single, and not multiple, administration of the anabolic steroid had a more rapid and more dramatic change on the neuropsychological level. It is believed that the anabolic steroids are responsible for the brain changes.

In a third study, a group of 14 adult male rats was divided into a control group (without any training) and a group consisting of 7-15% of rats who had been trained with a set of specific conditioning (a specific set of stimuli was given at a specific time). The control group received no stressor (no food, water, or any external stimuli other than light). The training was based on the rats’ ability to climb the “high wire” of light (high performance standard).

The control group was randomly assigned to receive (a) one-time treatment with a nonsteroidal anabolic steroid (i.e. a saline solution), or (b) a three-times-daily treatment for 1-5 days which consists of a low (i.e. 40 mg/kg), medium (41-50 mg/kg), or high (i.e. 80-90 mg/kg) dosing (maximum dose = 80 – 90 mg/kg).

Before starting the testing, the trained rats were subjected to an acute stress test. The control group was also subjected to the testing, in which the rats were subjected to a single stress test on the “high wire.” If the training was successful, then the trainees did not fare as well on the stress test compared to the trainees with no training. The groups consisted of control (n = 9), 3 months high dosing group (n = 7), and 2 months submaximal training group (n = 6).

For the acute stress tests, a maze (1 meter diameter, 50 cm high) was prepared at the beginning of the training period. The rats were allowed to enter the maze for 20 seconds (during which time the rats had to find the food that was hidden in the maze) and then left again for 20 seconds. At the end of the stress

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2016 · цитируется: 21 — supraphysiological administration of anabolic androgenic steroids has been linked to increased blood pressure. The widely distributed amino acid taurine. 2010 · цитируется: 116 — the use of anabolic-androgenic steroids (aas) by young athletes has been a primary concern of sports governing bodies because of the implications for unfair. 2002 · цитируется: 357 — testosterone actions represent the combination of several activities. First, it binds to the androgen receptor to exert its androgenic activity. — the anabolic androgenic steroids (aas) are a family of drugs that includes the male hormone testosterone and its synthetic derivatives

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