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Women are more likely to experience the development of masculine features with Winstrol, even at low doses, and this includes a lowering of the voice and development of body and facial hair. Hepatotoxicity ‘ Liver damage and changes to normal liver function are always a high risk with oral steroids as they must make a first pass through the liver. This is the big reason we limit Winstrol use to a maximum of 8 weeks (although 6 weeks is considered much safer) with at least the same amount of break time in between, allowing the liver to recover. Without recovery of the liver from the stress that Winstrol causes, liver failure can occur. Using a liver support product like N2Guard can go some way to protecting the liver during and after a Winstrol cycle. Increased Urination ‘ Winstrol has diuretic effects which is what makes it so powerful in shaping a lean, hard physique without water retention. 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